Hmg-Coa Synthase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  ASP-191   PHE-192  8.7 8.7 3.0 7.4 48.8 48.4 -24.3  PHE-192   TYR-193  7.6 7.5 12.7 -9.3 52.0 52.4 60.0  TYR-193   LYS-194  5.8 5.6 5.5 -4.9 26.7 25.1 -47.1 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  MET-215   ALA-216  5.2 5.4 -5.0 -8.9 82.4 87.9 7.9  ALA-216   LEU-217  1.7 1.7 7.6 -4.7 49.5 49.1 2.0  LEU-217   ASP-218  2.8 3.0 8.3 -6.0 24.0 25.4 24.3 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees