Insulin-Like Growth Factor 1 Receptor

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  ASN-478   THR-479  15.0 13.0 -11.7 -2.9 150.1 127.5 -14.9  THR-479   ARG-480  15.3 12.3 3.9 -3.1 90.3 126.5 3.2  ARG-480   ASN-481  14.2 12.8 -132.0 102.6 84.6 56.4 2.7  ASN-481   ASN-482  10.6 10.5 14.6 46.1 39.7 77.4 27.8  ASN-482   GLY-483  9.5 7.5 169.5 -57.6 50.3 34.3 97.3  GLY-483   GLU-484  12.9 7.5 -112.8 50.8 113.7 102.8 -38.2  GLU-484   ARG-485  13.3 10.3 -14.5 60.6 165.9 135.9 46.0  ARG-485   ALA-486  13.7 9.2 -33.5 92.3 136.4 124.3 -257.9  ALA-486   SER-487  10.9 6.5 -41.4 -15.1 112.2 150.0 219.5  SER-487   CYS-488  9.0 5.5 -74.1 -12.1 70.0 127.7 12.7  CYS-488   GLU-489  6.2 4.3 -27.5 -7.3 128.1 152.1 -4.3  GLU-489   SER-490  4.3 4.3 -43.0 35.2 103.0 104.9 -12.5 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees