Importin Beta-1 Subunit

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ALA-626   ALA-627  4.1 4.5 -9.8 6.0 37.2 44.5 32.9
 ALA-627   SER-628  4.3 5.3 -1.0 -5.9 102.8 102.6 -20.7
 SER-628   LEU-629  5.8 6.6 24.4 -18.9 54.9 41.8 33.2
 LEU-629   GLY-630  7.4 7.8 -11.7 9.3 67.5 77.0 -0.6
 GLY-630   LYS-631  9.4 10.1 0.7 -1.7 49.5 41.7 8.7
 LYS-631   GLY-632  12.2 12.7 -11.6 -1.4 154.0 148.8 -68.8
 GLY-632   PHE-633  10.1 10.4 2.4 1.2 71.6 80.8 12.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASN-649   GLN-650  20.2 19.6 3.6 0.8 111.4 111.8 -14.4
 GLN-650   VAL-651  19.8 19.0 -4.1 -3.4 6.9 13.3 53.8
 VAL-651   ASP-652  20.3 19.2 17.7 -14.1 125.0 132.0 -26.2
 ASP-652   SER-653  21.3 20.0 0.2 2.6 82.4 82.3 13.1
 SER-653   PRO-654  18.3 17.1 -0.6 1.2 66.2 71.3 -34.2
 PRO-654   VAL-655  14.8 13.6 4.6 -7.7 45.9 46.7 15.2
 VAL-655   SER-656  13.4 12.3 5.2 -7.3 95.6 93.7 -0.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-661   PHE-662  8.7 8.3 10.2 -10.3 37.4 34.1 2.3
 PHE-662   ILE-663  8.3 8.2 0.4 4.2 88.0 82.1 0.1
 ILE-663   ALA-664  11.8 11.9 2.3 -11.7 131.1 123.6 48.4
 ALA-664   ASP-665  10.9 11.3 6.4 2.5 66.0 64.3 14.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASP-679   ALA-680  23.2 23.6 -2.6 -1.4 78.5 84.3 29.7
 ALA-680   MET-681  21.6 21.6 -3.2 -4.4 135.1 143.3 -32.6
 MET-681   MET-682  19.1 19.1 3.3 7.8 38.4 35.3 68.5
 MET-682   ASN-683  21.7 21.8 -14.0 -3.9 84.4 86.7 -32.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-685   ALA-686  20.5 20.0 -6.5 18.2 48.7 54.0 -52.4
 ALA-686   GLN-687  24.0 23.6 -20.9 5.6 84.9 91.0 77.6
 GLN-687   MET-688  25.2 24.6 18.7 -22.0 120.5 116.2 -3.6
 MET-688   ILE-689  22.3 21.6 15.3 -15.3 160.1 173.3 -5.4
 ILE-689   SER-690  22.5 22.0 -1.0 -3.6 74.4 67.7 5.7
 SER-690   ASN-691  26.3 25.7 20.5 -21.0 57.0 64.0 -21.0
 ASN-691   PRO-692  26.2 25.4 -6.9 2.9 51.5 40.2 25.0
 PRO-692   ASN-693  28.0 26.9 -26.2 18.0 94.4 92.5 33.7
 ASN-693   ALA-694  25.6 25.2 -1.8 -0.8 78.4 92.2 1.3
 ALA-694   ARG-695  22.3 21.6 -5.9 0.2 42.8 37.3 60.8
 ARG-695   ARG-696  20.1 19.5 -5.6 5.0 38.0 52.0 -139.2
 ARG-696   GLU-697  19.0 18.1 4.8 2.3 80.9 81.6 -3.8
 GLU-697   LEU-698  15.3 14.6 1.5 -3.1 54.0 53.6 11.4
 LEU-698   LYS-699  16.4 16.0 -3.6 7.5 64.1 64.9 38.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees