Pyruvate Kinase, M2 Isozyme
(All numbering and residues are taken from first PDB file)
Bending Residue Dihedral Analysis
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
THR-114
LYS-115
6.1
6.4
-1.4
6.5
131.5
131.4
15.8
LYS-115
GLY-116
6.6
7.0
-4.0
18.2
104.1
106.9
35.9
GLY-116
PRO-117
3.5
3.7
-30.5
16.6
101.2
92.2
11.9
PRO-117
GLU-118
5.6
5.1
69.0
-51.9
30.8
27.4
74.6
GLU-118
ILE-119
7.6
7.9
9.5
-2.7
91.4
93.7
-13.9
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
PRO-219
ALA-220
7.2
7.4
23.5
-3.3
110.2
114.9
-20.5
ALA-220
VAL-221
4.5
4.7
17.2
-17.4
59.0
84.5
8.2
VAL-221
SER-222
2.4
2.2
52.0
-19.1
63.3
73.9
84.0
SER-222
GLU-223
5.1
5.2
-8.5
-6.9
153.3
155.3
-54.4
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees