DynDom - Protein Domain Motions

78 Kda Glucose-Regulated Protein

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	78 Kda Glucose-Regulated Protein
Conformer 1 (PDB)	6eof (A)
Conformer 2 (PDB)	6hab (A)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	372	3.95	31 - 408
2	112	3.79	414 - 525

Sequence

`________________________________________________________________________________________________________________________` `6eof(A) : TVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAM` `:` `6hab(A) : TVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVA----gERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDI--gQTKTFAPEEISAM` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `6eof(A) : VLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGAFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIK` `:` `6hab(A) : VLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIK` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `6eof(A) : LYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGI` `:` `6hab(A) : LYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGI` `________________________________________________________________________________________________________________________` `______________405_______________________________________________________________________________________________________` `6eof(A) : NPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGI` `:` `6hab(A) : NPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTFTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGI` `______________405_______________________________________________________________________________________________________` `________________________________________` `6eof(A) : LRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKF` `:` `6hab(A) : LRVTAEDKGTGNKNKITIT*********************` `________________________________________`

Morph

Jmol._Canvas2D (Jmol) "jmolApplet"[x]

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	126.0
Translation (A)	-27.0
Closure (%)	98.0
Bending Residues ( green )	405 - 417
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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