7 Alpha-Hydroxysteroid Dehydrogenase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name 7 Alpha-Hydroxysteroid Dehydrogenase
  Conformer 1
(PDB)
1fmc (B)
  Conformer 2
(PDB)
1ahh (A)
  Window Length 15
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 218 0.3   8 - 190   212 - 246
2 21 0.97   191 - 211

Sequence


           ________________________________________________________________________________________________________________________ 
 1fmc(B) : MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVF 
         :                                                                                                                          
 1ahh(A) : MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVF 
           ________________________________________________________________________________________________________________________ 

           _________________________________________________________________188____________________211_____________________________ 
 1fmc(B) : SFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVS 
         :                                                                                                                          
 1ahh(A) : SFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVS 
           _________________________________________________________________188____________________211_____________________________ 

           _______________                                                                                                          
 1fmc(B) : GQILTVSGGGVQELN                                                                                                          
         :                                                                                                                          
 1ahh(A) : GQILTVSGGGVQE**                                                                                                          
           _______________                                                                                                          

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
34.6
Translation
(A)
0.2
Closure
(%)
26.1
Bending Residues
( green )
  188 - 192
  211 - 215
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification:

No Contacts

PyMOL Script

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