Bira Bifunctional Protein (Acts As Biotin Operon Repressor 3 And Biotin Holoenzyme Synthetase) (E.C.6.3.4.15)

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Bira Bifunctional Protein (Acts As Biotin Operon Repressor 3 And Biotin Holoenzyme Synthetase) (E.C.6.3.4.15)
  Conformer 1
(PDB)
1bia  
  Conformer 2
(PDB)
2ewn (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 202 1.36   66 - 86   90 - 110   131 - 225   235 - 315
2 84 1.37   5 - 65   87 - 89   111 - 130   226 - 234

Sequence


           _______________________________________________________________65________________83_______________________109___________ 
 1bia    : MKDNTVPLKLIALLANGEFHSGEQLGETLGMSRAAINKHIQTLRDWGVDVFTVPGKGYSLPEPIQLLNAKQILGQLDGGSVAVLPVIDSTNQYLLDRIGELKSGDACIAEYQQAG----- 
         :                                                                                                                          
 2ewn(A) : **DNTVPLKLIALLANGEFHSGEQLGETLGMSRAAINKHIQTLRDWGVDVFTVPGKGYSLPEPIQLLNAKQILGQLDGGSVAVLPVIDSTNQYLLDRIGELKSGDACIAEYQQAGRGRRG 
           _______________________________________________________________65________________83_______________________109___________ 

           ____127______________________________________________________________________________________________224_______234______ 
 1bia    : ----sPFGANLYLSMFWRLEQ-pAAAIGLSLVIGIVMAEVLRKLGADKVRVKWPNDLYLQDRKLAGILVELTG----aAQIVIGAGINMAM-----------wITLQEAGINLDRNTLAA 
         :                                                                                                                          
 2ewn(A) : RKWFSPFGANLYLSMFWRLEQGPAAAIGLSLVIGIVMAEVLRKLGADKVRVKWPNDLYLQDRKLAGILVELTGKTGDAAQIVIGAGINMAMRRVEESVVNQGWITLQEAGINLDRNTLAA 
           ____127______________________________________________________________________________________________224_______234______ 

           ________________________________________________________________________________                                         
 1bia    : MLIRELRAALELFEQEGLAPYLSRWEKLDNFINRPVKLIIGDKEIFGISRGIDKQGALLLEQDGIIKPWMGGEISLR***                                         
         :                                                                                                                          
 2ewn(A) : MLIRELRAALELFEQEGLAPYLSRWEKLDNFINRPVKLIIGDKEIFGISRGIDKQGALLLEQDGIIKPWMGGEISLRSAE                                         
           ________________________________________________________________________________                                         

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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
15.4
Translation
(A)
-0.5
Closure
(%)
25.2
Bending Residues
( green )
  65 - 66
  83 - 90
  109 - 111
  127 - 132
  224 - 227
  234 - 235
Bending Region Analysis

Dynamic Contact Graph

The dynamic contact graph is still being generated. Progress: Initialising

PyMOL Script

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