Cyclin-Dependent Kinase 6 Inhibitor

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Cyclin-Dependent Kinase 6 Inhibitor
  Conformer 1
(PDB)
1g3n (F)
  Conformer 2
(PDB)
1mx2 (B)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 99 0.56   47 - 48   62 - 158
2 51 0.61   9 - 46   49 - 61

Sequence


           _______________________________________46_____________61________________________________________________________________ 
 1g3n(F) : GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKH 
         :                                                                                                                          
 1mx2(B) : *NELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGNAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKH 
           _______________________________________46_____________61________________________________________________________________ 

           _____________________________________                                                                                    
 1g3n(F) : TASNVGHRNHKGDTACDLARLYGRNEVVSLMQANG**                                                                                    
         :                                                                                                                          
 1mx2(B) : TASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAG                                                                                    
           _____________________________________                                                                                    

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
11.6
Translation
(A)
-0.1
Closure
(%)
98.2
Bending Residues
( green )
  46 - 49
  61 - 63
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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