Elongation Factor G

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Elongation Factor G
  Conformer 1
(PDB)
2bm1 (A)
  Conformer 2
(PDB)
1ktv (B)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 498 2.25   7 - 482   604 - 647   650 - 674   679 - 684
2 127 0.78   483 - 603   648 - 649   675 - 678

Sequence


           ________________________________________________________________________________________________________________________ 
 2bm1(A) : KVEYDLKRLRNIVIAAHIDAGKTTTTERILYYTGRIiTAAVTTCFWKDHRINIIDTPGHVDFTIEVERSMRVLDGAIVVFDSSQGVEPQSETVWRQAEKYKVPRIAFANKMDKTGADLWL 
         :                                                                                                                          
 1ktv(B) : *VEYDLKRLRNIGIAAHIDAGKTTTTERILYYTGRI---aVTTCFWKDHRINIIDTPGHVDFTIEVERSMRVLDGAIVVFDSSQGVEPQSETVWRQAEKYKVPRIAFANKMDKTGADLWL 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 2bm1(A) : VIRTMQERLGARPVVMQLPIGREDTFSGIIDVLRMKAYTYGNDLGTDIREIPIPEEYLDQAREYHEKLVEVAADFDENIMLKYLEGEEPTEEELVAAIRKGTIDLKITPVFLGSALKNKG 
         :                                                                                                                          
 1ktv(B) : VIRTMQERLGARPVVMQLPIGREDTFSGIIDVLRMKAYTYGNDLGTDIREIPIPEEYLDQAREYHEKLVEVAADFDENIMLKYLEGEEPTEEELVAAIRKGTIDLKITPVFLGSALKNKG 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 2bm1(A) : VQLLLDAVVDYLPSPLDIPPIKGTTPEGEVVEIHPDPNGPLAALAFKIMADPYVGRLTFIRVYSGTLTSGSYVYNTTKGRKERVARLLRMHANHREEVEELKAGDLGAVVGLKETITGDT 
         :                                                                                                                          
 1ktv(B) : VQLLLDAVVDYLPSPLDIPPIKGTTPEGEVVEIHPDPNGPLAALAFKIMADPYVGRLTFIRVYSGTLTSGSYVYNTTKGRKERVARLLRMHANHREEVEELKAGDLGAVVGLKETITGDT 
           ________________________________________________________________________________________________________________________ 

           ___________________________________________________________________________________________482__________________________ 
 2bm1(A) : LVGEDAPRVILESIEVPEPVIDVAIEPKTKADQEKLSQALARLAEEDPTFRVSTHPETGQTIISGMGELHLEIIVDRLKREFKVDANVGKPQVAYRETITKPVDVEGKFIRQTGGRGQYG 
         :                                                                                                                          
 1ktv(B) : LVGEDAPRVIL---------iDVAIEPK--------sQALARLAEEDPTFRVSTHP---qTIISGMGELHLEIIVDRLKREF-----vGKPQVAYRETITKPVDVEGKFIRQTGGRGQYG 
           ___________________________________________________________________________________________482__________________________ 

           ____________________________________________________________________________________________603_________________________ 
 2bm1(A) : HVKIKVEPLPRGSGFEFVNAIVGGVIPKEYIPAVQKGIEEAMQSGPLIGFPVVDIKVTLYDGSYHEVDSSEMAFKIAGSMAIKEAVQKGDPVILEPIMRVEVTTPEEYMGDVIGDLNARR 
         :                                                                                                                          
 1ktv(B) : HVKIKVEPLPRGSGFEFVNAIVGGVIPKEYIPAVQKGIEEAMQSGPLIGFPVVDIKVTLYDGSYHEVDSSEMAFKIAGSMAIKEAVQKGDPVILEPIMRVEVTTPEEYMGDVIGDLNARR 
           ____________________________________________________________________________________________603_________________________ 

           ________________647________________________674_678___________                                                            
 2bm1(A) : GQILGMEPRGNAQVIRAFVPLAEMFGYATDLRSKTQGRGSFVMFFDHYQEVPKQVQEKLI*                                                            
         :                                                                                                                          
 1ktv(B) : GQILGMEPRGNAQVIRAFVPLAEMFGYATDLRSKTQGRGSFVMFFDHYQEVPKQVQEKLIK                                                            
           ________________647________________________674_678___________                                                            

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
14.8
Translation
(A)
2.4
Closure
(%)
37.2
Bending Residues
( green )
  482 - 483
  603 - 604
  647 - 650
  674 - 675
  678 - 679
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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