Focal Adhesion Kinase 1

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Focal Adhesion Kinase 1
  Conformer 1
(PDB)
1mp8 (A)
  Conformer 2
(PDB)
2etm (B)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 161 0.41   502 - 560   564 - 684
2 87 0.7   416 - 501   561 - 563

Sequence


           ______________________________________________________________________________________501_______________________________ 
 1mp8(A) : *DYEIQRERIELGRCIGEGQFGDVHQGIYMSP--pALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLST 
         :                                                                                                                          
 2etm(B) : RDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLST 
           ______________________________________________________________________________________501_______________________________ 

           _________________________560____________________________________________________________________________________________ 
 1mp8(A) : ALAYLESKRFVHRDIAARNVLVSSNDCVKLGD-----lPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRR 
         :                                                                                                                          
 2etm(B) : ALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRlPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRR 
           _________________________560____________________________________________________________________________________________ 

           _______________________                                                                                                  
 1mp8(A) : PRFTELKAQLSTILEEEKAQ***                                                                                                  
         :                                                                                                                          
 2etm(B) : PRFTELKAQLSTILEEEKAQQEE                                                                                                  
           _______________________                                                                                                  

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
For more advanced options, right click on the model.


Show console


play backwards pause play forwards

Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
6.5
Translation
(A)
-0.2
Closure
(%)
65.2
Bending Residues
( green )
  501 - 504
  560 - 561
  563 - 564
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

Download and extract PyMOL PML script file Download