Fructose-1,6-Bisphosphatase (D-Fructose-1,6-Bisphosphate 3 1-Phosphohydrolase) (E.C.3.1.3.11)

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Fructose-1,6-Bisphosphatase (D-Fructose-1,6-Bisphosphate 3 1-Phosphohydrolase) (E.C.3.1.3.11)
  Conformer 1
(PDB) 		1spi (A)
  Conformer 2
(PDB) 		1spi (D)
  Window Length 15
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 290 1.39   18 - 154   179 - 351
2 24 4.38   155 - 178

Sequence


           ________________________________________________________________________________________________________________________ 
 1spi(A) : AATQTKARTRSKYEIETLTGWLLKQPMAGVIDAELTIVLSSISLACKQIASLVQRAkLDVVSNEVFSSCLRSSGRTGIIASEEEDVPVAVEESYSGNYIVVFDPLDGSSNIDAAVSTGSI 
         :                                                                                                                          
 1spi(D) : *****KARTRSKYEIETLTGWLLKQPMAGVIDAELTIVLSSISLACKQIASLVQRAkLDVVSNEVFSSCLRSSGRTGIIASEEEDVPVAVEESYSGNYIVVFDPLDGSSNIDAAVSTGSI 
           ________________________________________________________________________________________________________________________ 

           ____152_______________________178_______________________________________________________________________________________ 
 1spi(A) : FGIYSPNDECIVDSDHDDESQLSAEEQRCVVNVCQPGDNLLAAGYCMYSSSVIFVLTIGKGVYAFTLDPMYGEFVLTSEKIQIPKAGKIYSFNEGNYKMWPDKLKKYMDDLKEPGESQKP 
         :                                                                                                                          
 1spi(D) : FGIYSPNDECIVDSDHDDESQLSAEEQRCVVNVCQPGDNLLAAGYCMYSSSVIFVLTIGKGVYAFTLDPMYGEFVLTSEKIQIPKAGKIYSFNEGNYKMWPDKLKKYMDDLKEPGESQKP 
           ____152_______________________178_______________________________________________________________________________________ 

           _____________________________________________________________________________________________                            
 1spi(A) : YSSRYIGSLVGDFHRTLLYGGIYGYPRDAKSKNGKLRLLYECAPMSFIVEQAGGKGSDGHQRILDIQPTEIHQRVPLYIGSVEEVEKLEKYLA                            
         :                                                                                                                          
 1spi(D) : YSSRYIGSLVGDFHRTLLYGGIYGYPRDAKSKNGKLRLLYECAPMSFIVEQAGGKGSDGHQRILDIQPTEIHQRVPLYIGSVEEVEKLEKYLA                            
           _____________________________________________________________________________________________                            

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		97.6
Translation
(A) 		4.3
Closure
(%) 		4.4
Bending Residues
( green ) 		  152 - 155
  178 - 182
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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