Gephyrin

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Gephyrin
  Conformer 1
(PDB)
1t3e (A)
  Conformer 2
(PDB)
2fu3 (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 315 0.87   320 - 367   461 - 734
2 79 1.0   368 - 460

Sequence


           _____________________________________________365________________________________________________________________________ 
 1t3e(A) : MSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESD 
         :                                                                                                                          
 2fu3(A) : MSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIG----------tVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRES- 
           _____________________________________________365________________________________________________________________________ 

           ____________________460_________________________________________________________________________________________________ 
 1t3e(A) : DGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNA 
         :                                                                                                                          
 2fu3(A) : ---eELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNA 
           ____________________460_________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 1t3e(A) : LNEGISRADVIITSGGV-----dYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCI 
         :                                                                                                                          
 2fu3(A) : LNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCI 
           ________________________________________________________________________________________________________________________ 

           ___________________________________________________________                                                              
 1t3e(A) : LTWHHQEPLPWAQSTGNQMS--lMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL                                                              
         :                                                                                                                          
 2fu3(A) : LTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL                                                              
           ___________________________________________________________                                                              

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
27.2
Translation
(A)
1.2
Closure
(%)
89.7
Bending Residues
( green )
  365 - 368
  460 - 462
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification:

No Contacts

PyMOL Script

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