Humanized Antibody Hfe7a, Light Chain

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Humanized Antibody Hfe7a, Light Chain
  Conformer 1
(PDB) 		1it9 (L)
  Conformer 2
(PDB) 		2gcy (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 107 0.93   3 - 109
2 103 0.92   110 - 212

Sequence


           _________________________________________________________________________________________________________108____________ 
 1it9(L) : EIVLTQSPGTLSLSPGERATLSCKASQSVDYDGDSYMNWYQQKPGQAPRLLIYAASNLESGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQSNEDPRTFGQGTKLEIKRTVAAPSVF 
         :                                                                                                                          
 2gcy(A) : EIVLTQSPATLSLSPGERATISCRASESVDSYGHSFMQWYQQKPGQAPRLLIYRASNLEPGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQSNEAPFTFGQGTKVEIKRTVAAPSVF 
           _________________________________________________________________________________________________________108____________ 

           ________________________________________________________________________________________________                         
 1it9(L) : IFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFN**                         
         :                                                                                                                          
 2gcy(A) : IFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRG                         
           ________________________________________________________________________________________________                         

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		30.4
Translation
(A) 		-0.3
Closure
(%) 		85.1
Bending Residues
( green ) 		  108 - 110
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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