Hypoxanthine-Guanine Phosphoribosyltransferase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Hypoxanthine-Guanine Phosphoribosyltransferase
  Conformer 1
(PDB)
1z7g (C)
  Conformer 2
(PDB)
1hmp (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 101 0.63   6 - 9   12 - 47   58 - 77   94 - 98   163 - 163   165 - 165   182 - 215
2 86 0.83   10 - 11   48 - 57   78 - 93   122 - 162   164 - 164   166 - 181

Sequence


           _____9____________________________________47________57__________________77______________93___98_________________________ 
 1z7g(C) : SPGVVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLK----------iKVIGGDDLST 
         :                                                                                                                          
 1hmp(A) : SPGVVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLST 
           _____9____________________________________47________57__________________77______________93___98_________________________ 

           ____________________________________162________________181____________________________________                           
 1z7g(C) : LTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA                           
         :                                                                                                                          
 1hmp(A) : LTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA                           
           ____________________________________162________________181____________________________________                           

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
7.7
Translation
(A)
-0.2
Closure
(%)
83.4
Bending Residues
( green )
  9 - 12
  47 - 48
  57 - 58
  77 - 78
  93 - 94
  98 - 122
  162 - 166
  181 - 182
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

PyMOL Script

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