Kinesin-Related Motor Protein Eg5

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Kinesin-Related Motor Protein Eg5
  Conformer 1
(PDB)
1ii6 (A)
  Conformer 2
(PDB)
2ieh (A)
  Window Length 9
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 275 2.09   22 - 181   185 - 267   323 - 354
2 34 0.98   182 - 184   292 - 322

Sequence


           ________________________________________________________________________________________________________________________ 
 1ii6(A) : *GKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAG 
         :                                                                                                                          
 2ieh(A) : KGKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAG 
           ________________________________________________________________________________________________________________________ 

           ____________________________________________181_________________________________________________________________________ 
 1ii6(A) : IIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEE 
         :                                                                                                                          
 2ieh(A) : IIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEE 
           ____________________________________________181_________________________________________________________________________ 

           __________267_________________________________________321____________________________________________                    
 1ii6(A) : LVKIGKLNLVDLAGSErAREAGNINQSLLTLGRVITALVERTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPEV                    
         :                                                                                                                          
 2ieh(A) : LVKIGKLNLVDLAGSE------NiNQSLLTLGRVITALVERTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPE*                    
           __________267_________________________________________321____________________________________________                    

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
15.5
Translation
(A)
0.5
Closure
(%)
46.1
Bending Residues
( green )
  181 - 185
  267 - 292
  321 - 323
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

PyMOL Script

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