Flp Recombinase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Flp Recombinase
  Conformer 1
(PDB)
1p4e (D)
  Conformer 2
(PDB)
1flo (D)
  Window Length 11
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 366 0.82   7 - 107   143 - 417
2 22 3.93   108 - 142

Sequence


           ___________________________________________________________________________________________________103__________________ 
 1p4e(D) : SQFDILCKTPPKVLVRQFVERFERPSGEKIASCAAELTYLCWMITHNGTAIKRATFMSYNTIISNSLSFDIVNKSLQFKYKTQKATILEASLKKLIPAWEFTIIPY-----NsDITDIVS 
         :                                                                                                                          
 1flo(D) : PQFDILCKTPPKVLVRQFVERFERPSGEKIALCAAELTYLCWMITHNGTAIKRATFMSYNTIISNSLSFDIVNKSLQFKYKTQKATILEASLKKLIPAWEFTIIPYYGQKHQSDITDIVS 
           ___________________________________________________________________________________________________103__________________ 

           _____________142________________________________________________________________________________________________________ 
 1p4e(D) : SLQLQFESSgNSHSKKMLKALLSEGESIWEITEKILNSFEYTSRFTKTKTLYQFLFLATFINCGRFSDIKNVDPKSFKLVQNKYLGVIIQCLVTETKTSVSRHIYFFSARGRIDPLVYLD 
         :                                                                                                                          
 1flo(D) : SLQLQFESs---HSKKMLKALLSEGESIWEITEKILNSFEYTSRFTKTKTLYQFLFLATFINCGRFSDIKNVDPKSFKLVQNKYLGVIIQCLVTETKTSVSRHIYFFSARGRIDPLVYLD 
           _____________142________________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 1p4e(D) : EFLRNSEPVLKRVNRTGNsNKQEYQLLKDNLVRSYNKALKKNAPYPIFAIKNGPKSHIGRHLMTSFLSMKGLTELTNVVGNFSDKRASAVARTT-tHQITAIPDHYFALVSRYYAYDPIS 
         :                                                                                                                          
 1flo(D) : EFLRNSEPVLKRVNRTGsSNKQEYQLLKDNLVRSYNKALKKNAPYSIFAIKNGPKSHIGRHLMTSFLSMKGLTELTNVVGNWSDKRASAVARTTYTHQITAIPDHYFALVSRYYAYDPIS 
           ________________________________________________________________________________________________________________________ 

           _______________________________________________________                                                                  
 1p4e(D) : KEMIALKDETNPIEEWQHIEQLKGSAEGSIRYPAWNGIISQEVLDYLSSYINRR*                                                                  
         :                                                                                                                          
 1flo(D) : KEMIALKDETNPIEEWQHIEQ-------sIRYPAWNGIISQEVLDYLSSYINRRI                                                                  
           _______________________________________________________                                                                  

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
23.9
Translation
(A)
0.1
Closure
(%)
64.2
Bending Residues
( green )
  103 - 108
  142 - 144
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Mixed

PyMOL Script

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