Atp-Dependent RNA Helicase Dob1

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Atp-Dependent RNA Helicase Dob1
  Conformer 1
(PDB)
5ooq (B)
  Conformer 2
(PDB)
6ieh (B)
  Window Length 7
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 658 2.56   119 - 618   620 - 620   731 - 742   871 - 1062
2 231 2.64   619 - 619   621 - 730   743 - 870

Sequence


           ________________________________________________________________________________________________________________________ 
 5ooq(B) : MLADSFEQEASREVDASKGLTNSETLQVEQDGKVRLSHQVRHQVALPPNYDYTPIAp----------FTLDPFQDTAISCIDRGESVLVSAHTSAGKTVVAEYAIAQSLKNKQRVIYTSP 
         :                                                                                                                          
 6ieh(B) : ***************************RVKVQSVETVEGCTHEVALPAEEDYLPLKPRVGKAAKEYPFILDAFQREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALREKQRVIFTSP 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 5ooq(B) : IKALSNQKYRELLAEFGDVGLMTGDITINPDAGCLVMTTEILRSMLYRGSEVMREVAWVIFDEVHYMRDKERGVVWEETIILLPDKVRYVFLSATIPNAMEFAEWICKIHSQPCHIVYTN 
         :                                                                                                                          
 6ieh(B) : IKALSNQKYREMYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQPCHVIYTD 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 5ooq(B) : FRPTPLQHYLFPAHGDGIYLVVDEKSTFREENFQKAMASI-SkGD--IYKIVKMIWKKKYNPVIVFSFSKRDCEELALKMSKLDFNSDDEKEALTKIFNNAIALLPETDRELPQIKHILP 
         :                                                                                                                          
 6ieh(B) : YRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDsNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVEHVLP 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 5ooq(B) : LLRRGIGIHHSGLLPILKEVIEILFQEGFLKVLFATETF---lNMPAKTVVFTSVRKWDGQQFRWVSGGEYIQMSGRAGRRGLDDRGIVIMMIDEKMEPQVAKGMVKGQADRLDSAFHLG 
         :                                                                                                                          
 6ieh(B) : LLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADPLNSAFHLT 
           ________________________________________________________________________________________________________________________ 

           _____________________________618________________________________________________________________________________________ 
 5ooq(B) : YNMILNLMRVEGISPEFMLEHSFFQFQNVISVPVMEKKLAELKKDFDGIEVEDEENVKEYHEIEQAIKGYREDVRQVVTHPANALSFLQPGRLVEISVNGKDNYGWGAVVDFAKRIN-nP 
         :                                                                                                                          
 6ieh(B) : YNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQYNKIVIPNEESVVIYYKIRQQLAKLGKEIEEYIHKPKYCLPFLQPGRLVKVKNEG-DDFGWGVVVNFSKKSNVKP 
           _____________________________598________________________________________________________________________________________ 

           ______________724_______________________________________________________________________________________________________ 
 5ooq(B) : SAVYTDHESYIVNVVVNTMYIDSPVNLLKPFNPTLPEGIRPAEEGEKSICAVIPITLDSIKSIGNLRLYMPKDIRASGQKETVGKSLREVNRRFPDGIPVLDPVKNMKIEDEDFLKLMKK 
         :                                                                                                                          
 6ieh(B) : NSGELD-PLYVVEVLLRC----SKESL----KNSATEAAKPAKPDEKGEMQVVPVLVHLLSAISSVRLYIPKDLRPVDNRQSVLKSIQEVQKRFPDGIPLLDPIDDMGIQDQGLKKVIQK 
           ______________701_______________________________________________________________________________________________________ 

           ________________________________________870_____________________________________________________________________________ 
 5ooq(B) : IDVLNTKLSSNPLTNSMRLEELYGKYSRKHDLHEDMKQLKRKISESQAVIQLDDLRRRKRVLRRLGFCTPNDIIELKGRVACEISSGDELLLTELIFNGNFNELKPEQAAALLSCFAFQE 
         :                                                                                                                          
 6ieh(B) : VEAFEHRMYSHPLHNDPNLETVYTLCEKKAQIAIDIKSAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMFNGLFNDLSAEQATALLSCFVFQE 
           ________________________________________839_____________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 5ooq(B) : RCKEAPRLKPELAEPLKAMREIAAKIAKIMKDSKIEVVEKDYVESFRHELMEVVYEWCRGATFTQICKMTDVYEGSLIRMFKRLEELVKELVDVANTIGNSSLKEKMEAVLKLIHRDIVS 
         :                                                                                                                          
 6ieh(B) : NSSEMPKLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHICKMTDVFEGSIIRCMRRLEELLRQMCQAAKAIGNTELENKFAEGITKIKRDIVF 
           ________________________________________________________________________________________________________________________ 

           ______                                                                                                                   
 5ooq(B) : AGSLYL                                                                                                                   
         :                                                                                                                          
 6ieh(B) : AASLYL                                                                                                                   
           ______                                                                                                                   

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
20.5
Translation
(A)
1.3
Closure
(%)
44.9
Bending Residues
( green )
  618 - 621
  724 - 745
  870 - 874
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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