Light Chain Of Nivolumab

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Light Chain Of Nivolumab
  Conformer 1
(PDB) 		5wt9 (L)
  Conformer 2
(PDB) 		7k3q (L)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 106 0.46   106 - 211
2 101 1.15   3 - 105

Sequence


           _____________________________________________________________________________________________________________105________ 
 5wt9(L) : STGEIVLTQSPATLSLSPGERATLSCRASQSVSS-YLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQS---SNWPRTFGQGTKVEIKRTVAAP 
         :                                                                                                                          
 7k3q(L) : ***DIVLTQTPGTLSLSPGERATLSCRASQSVSSSYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQYVGLTGW--TFGQGTKVEIKRTVAAP 
           _____________________________________________________________________________________________________________107________ 

           _____________________________________________________________________________________________________                    
 5wt9(L) : SVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE*                    
         :                                                                                                                          
 7k3q(L) : SVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC                    
           _____________________________________________________________________________________________________                    

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		9.6
Translation
(A) 		0.3
Closure
(%) 		5.7
Bending Residues
( green ) 		  105 - 108
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Mixed

PyMOL Script

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