DynDom - Protein Domain Motions

Alcohol Dehydrogenase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Alcohol Dehydrogenase
Conformer 1 (PDB)	1qlj (A)
Conformer 2 (PDB)	1p1r (A)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	229	0.59	3 - 177 291 - 291 293 - 296 319 - 337 339 - 339 344 - 372
2	141	0.41	178 - 290 292 - 292 297 - 318 338 - 338 340 - 343

Sequence

`________________________________________________________________________________________________________________________` `1qlj(A) : STAGKVIKCKAAVLWEEKKPFSIEEVEVAPPKAHEVRIKMVATGICRSDDHVVSGTLVTPLPVIAGHEAAGIVESIGEGVTTVRPGDKVIPLFTPQCGKCRVCKHPEGNFCLKNDLSMPR` `:` `1p1r(A) : STAGKVIKCKAAVLWEEKKPFSIEEVEVAPPKAHEVRIKMVATGICRSDDHVVSGTLVTPLPVIAGHEAAGIVESIGEGVTTVRPGDKVIPLFTPQCGKCRVCKHPEGNFCLKNDLSMPR` `________________________________________________________________________________________________________________________` `______________________________________________________177_______________________________________________________________` `1qlj(A) : GTMQDGTSRFTCRGKPIHHFLGTSTFSQYTVVDEISVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTQGSTCAVFGLGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVGATEC` `:` `1p1r(A) : GTMQDGTSRFTCRGKPIHHFLGTSTFSQYTVVDEISVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTQGSTCAVFGLGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVGATEC` `______________________________________________________177_______________________________________________________________` `_______________________________________________290_________________________318_______________336____343_________________` `1qlj(A) : VNPQDYKKPIQEVLTEMSNGGVDFSFEVIGRLDTMVTALSCCQEAYGVSVIVAVTPDSQNLSMNPMLLLSGRTWKGAIFGGFKSKDSVPKLVADFMAKKFALDPLITHVLPFEKINEGFD` `:` `1p1r(A) : VNPQDYKKPIQEVLTEMSNGGVDFSFEVIGRLDTMVTALSCCQEAYGVSVIVGVPPDSQNLSMNPMLLLSGRTWKGAIFGGFKSKDSVPKLVADFMAKKFALDPLITHVLPFEKINEGFD` `_______________________________________________290_________________________318_______________336____343_________________` `______________` `1qlj(A) : LLRSGESIRTILTF` `:` `1p1r(A) : LLRSGESIRTILTF` `______________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	6.9
Translation (A)	-0.6
Closure (%)	99.2
Bending Residues ( green )	177 - 178 290 - 300 318 - 319 336 - 340 343 - 344
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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