DynDom - Protein Domain Motions

Alcohol Dehydrogenase Class III Chi Chain

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Alcohol Dehydrogenase Class III Chi Chain
Conformer 1 (PDB)	1mc5 (A)
Conformer 2 (PDB)	1mc5 (B)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	190	0.3	91 - 93 98 - 108 164 - 294 297 - 322 331 - 333 336 - 338 342 - 345 358 - 362 366 - 369
2	179	0.46	3 - 90 94 - 97 109 - 163 295 - 296 323 - 330 334 - 335 339 - 341 346 - 357 363 - 365 370 - 371

Sequence

`________________________________________________________________________________________90_93__97________108____________` `1mc5(A) : ANEVIKCKAAVAWEAGKPLSIEEIEVAPPKAHEVRIKIIATAVCHTDAYTLSGADPEGCFPVILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQGKG` `:` `1mc5(B) : ANEVIKCKAAVAWEAGKPLSIEEIEVAPPKAHEVRIKIIATAVCHTDAYTLSGADPEGCFPVILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQGKG` `________________________________________________________________________________________90_93__97________108____________` `________________________________________163_____________________________________________________________________________` `1mc5(A) : LMPDGTSRFTCKGKTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGISTGYGAAVNTAKLEPGSVCAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFARAKEFGATECI` `:` `1mc5(B) : LMPDGTSRFTCKGKTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGISTGYGAAVNTAKLEPGSVCAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFARAKEFGATECI` `________________________________________163_____________________________________________________________________________` `_________________________________________________292__________________________321______330_____338____345_________357___` `1mc5(A) : NPQDFSKPIQEVLIEMTDGGVDYSFECIGNVKVMRAALEACHKGWGVSVVVGVAASGEEIATRPFQLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTHNLSFDEINKAFEL` `:` `1mc5(B) : NPQDFSKPIQEVLIEMTDGGVDYSFECIGNVKVMRAALEACHKGWGVSVVVGVAASGEEIATRPFQLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTHNLSFDEINKAFEL` `_________________________________________________292__________________________321______330_____338____345_________357___` `______369____` `1mc5(A) : MHSGKSIRTVVKI` `:` `1mc5(B) : MHSGKSIRTVVKI` `______369____`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	4.4
Translation (A)	0.1
Closure (%)	99.4
Bending Residues ( green )	90 - 91 93 - 94 97 - 99 108 - 109 163 - 165 292 - 297 321 - 323 330 - 336 338 - 339 341 - 342 345 - 346 357 - 366 369 - 370
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

PyMOL Script

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