Alcohol Dehydrogenase Class III

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Alcohol Dehydrogenase Class III
  Conformer 1
(PDB) 		4dlb (A)
  Conformer 2
(PDB) 		4dla (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 186 0.33   5 - 15   19 - 48   62 - 178   326 - 329   332 - 337   341 - 342   345 - 348   353 - 359   373 - 377
2 27 0.64   16 - 18   49 - 61   360 - 370
3 160 0.26   179 - 325   330 - 331   338 - 340   343 - 344   349 - 352   371 - 372

Sequence


           _____________15_18____________________________48___________61___________________________________________________________ 
 4dlb(A) : SATQGQVITCKAAVAWEPNKPLVIEDVQVAPPQAGEVRVKVLYTALCHTDAYTWSGKDPEGLFPCVLGHEAAGIVESVGEGVTEVQPGDHVIPCYQAECRECKFCKSGKTNLCGKVRAAT 
         :                                                                                                                          
 4dla(A) : SATQGQVITCKAAVAWEPNKPLVIEDVQVAPPQAGEVRVKVLYTALCHTDAYTWSGKDPEGLFPCVLGHEAAGIVESVGEGVTEVQPGDHVIPCYQAECRECKFCKSGKTNLCGKVRAAT 
           _____________15_18____________________________48___________61___________________________________________________________ 

           _______________________________________________________178______________________________________________________________ 
 4dlb(A) : GVGVMMNDRKSRFSINGKPIYHFMGTSTFSQYTVVHDVSVAKIDPVAPLEKVCLLGCGVPTGLGAVWNTAKVEPGSIVAVFGLGTVGLAVAEGAKAAGASRIIGIDIDSKKFDRAKNFGV 
         :                                                                                                                          
 4dla(A) : GVGVMMNDRKSRFSINGKPIYHFMGTSTFSQYTVVHDVSVAKIDPVAPLEKVCLLGCGVPTGLGAVWNTAKVEPGSIVAVFGLGTVGLAVAEGAKAAGASRIIGIDIDSKKFDRAKNFGV 
           _______________________________________________________178______________________________________________________________ 

           __________________________________________________________________________________325_329_____337________348_352____359_ 
 4dlb(A) : TEFINPKEHEQPIQQVIVDLTDGGVDYSFECIGNVSVMRSALECCHKGWGTSVIVGVAASGQEISTRPFQLVTGRVWKGTAFGGFKSRSQVPSLVDKYLKKEIKVDEYITHNMTLADINK 
         :                                                                                                                          
 4dla(A) : TEFINPKEHEQPIQQVIVDLTDGGVDYSFECIGNVSVMRSALECCHKGWGTSVIVGVAASGQEISTRPFQLVTGRVWKGTAFGGFKSRSQVPSLVDKYLKKEIKVDEYITHNMTLADINK 
           __________________________________________________________________________________325_329_____337________348_352____359_ 

           ________371________                                                                                                      
 4dlb(A) : AFDLMHDGDCLRVVLDMFV                                                                                                      
         :                                                                                                                          
 4dla(A) : AFDLMHDGDCLRVVLDMFV                                                                                                      
           ________371________                                                                                                      

Morph

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Domain Pairs

Fixed Domain Moving Domain Rotation Angle Translation   (A) Closure Bending Residues  
1 2 6.2 0.0 14.3   15 - 16   18 - 19   48 - 49   61 - 62   359 - 360 Bending Region Analysis
1 3 3.5 0.1 89.8   178 - 179   325 - 326   329 - 332   337 - 345   348 - 349   352 - 353   371 - 373 Bending Region Analysis
2 3 8.8 -0.7 97.1   368 - 372 Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

Conformer 1 Contact:
Residue 1 ———› Residue 3

Conformer 2 Contact:
Residue 3 ———› Residue 1

Movement classification:

No Contacts

Conformer 1 Contact:
Residue 3 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 3

Movement classification: Hinge

PyMOL Script

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