Atp-Dependent RNA Helicase Ddx3x

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Atp-Dependent RNA Helicase Ddx3x
  Conformer 1
(PDB) 		4pxa (A)
  Conformer 2
(PDB) 		5e7i (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 261 0.68   137 - 411
2 163 1.6   412 - 574

Sequence


           ________________________________________________________________________________________________________________________ 
 4pxa(A) : *DWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRA 
         :                                                                                                                          
 5e7i(A) : DDWSKPLPPSERLEQELFSG----------dDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRA 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 4pxa(A) : MKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLVMGFEPQIRRIVEQDTMPPK 
         :                                                                                                                          
 5e7i(A) : MKE----gRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPK 
           ________________________________________________________________________________________________________________________ 

           ___________________________________411__________________________________________________________________________________ 
 4pxa(A) : GVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSP 
         :                                                                                                                          
 5e7i(A) : GVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSP 
           ___________________________________411__________________________________________________________________________________ 

           ____________________________________________________________________________________                                     
 4pxa(A) : ILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAY*                                     
         :                                                                                                                          
 5e7i(A) : ILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYE                                     
           ____________________________________________________________________________________                                     

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		16.5
Translation
(A) 		1.9
Closure
(%) 		77.6
Bending Residues
( green ) 		  411 - 412
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Mixed

PyMOL Script

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