DynDom - Protein Domain Motions

Bifunctional Protein Puta

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Bifunctional Protein Puta
Conformer 1 (PDB)	6x9a (A)
Conformer 2 (PDB)	9bbo (B)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	950	0.39	18 - 577 587 - 607 621 - 696 701 - 724 730 - 742 745 - 756 761 - 764 775 - 775 810 - 959 961 - 961 965 - 966 970 - 1009 1015 - 1015 1021 - 1039 1081 - 1095 1214 - 1231
2	257	0.36	578 - 586 608 - 620 697 - 700 725 - 729 743 - 744 757 - 760 765 - 774 776 - 809 960 - 960 962 - 964 967 - 969 1010 - 1014 1016 - 1020 1040 - 1080 1096 - 1213

Sequence

`________________________________________________________________________________________________________________________` `6x9a(A) : APAPFADFAPPVRPQSTLRRAITAAYRRPETECLPPLVEAATQSKEIRDAAASTARKLIEALRGK----gVEGLVQEYSLSSQEGVALMCLAEALLRIPDTATRDALIRDKIADGNWKSH` `:` `9bbo(B) : *PAPFADFAPPVRPQSTLRRAITAAYRRPETECLPPLVEAATQSKEIRDAAASTARKLIEALRGKHSGSGVEGLVQEYSLSSQEGVALMCLAEALLRIPDTATRDALIRDKIAD-nWKSH` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `6x9a(A) : L--sRSLFVNAATWGLVVTGKLTSTVNDRSLAAALTRLISRCGEPVIRRGVDMAMRMMGEQFVTGETIREALKRSKELEEKGFSYSYDMLGEAATTAADAERYYRDYESAIHAIGKASAG` `:` `9bbo(B) : LGGSRSLFVNAATWGLVVTGKLTSTVNDRSLAAALTRLISRCGEPVIRRGVDMAMRMMGEQFVTGETIREALKRSKELEEKGFSYSYDMLGEAATTAADAERYYRDYESAIHAIGKASAG` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `6x9a(A) : RGIYEGPGISIKLSALHPRYSRAQAARVMGELLPRVKALALLAKNYDIGLNIDAEEADRLELSLDLLEVLCLDGDLSGWNGMGFVVQAYGKRCPFVLDFIIDLARRSGRRIMVRLVKGAY` `:` `9bbo(B) : RGIYEGPGISIKLSALHPRYSRAQAARVMGELLPRVKALALLAKNYDIGLNIDAEEADRLELSLDLLEVLCLDGDLSGWNGMGFVVQAYGKRCPFVLDFIIDLARRSGRRIMVRLVKGAY` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `6x9a(A) : WDAEIKRAQLDGLADFPVFTRKIHTDVSYIACAAKLLAATDVVFPQFATHNAQTLAAIYHMAGKDFHVGKYEFQCLHGMGEPLYEEVVGRGKLDRPCRIYAPVGTHETLLAYLVRRLLEN` `:` `9bbo(B) : WDAEIKRAQLDGLADFPVFTRKIHTDVSYIACAAKLLAATDVVFPQFATHNAQTLAAIYHMAGKDFHVGKYEFQCLHGMGEPLYEEVVGRGKLDRPCRIYAPVGTHETLLAYLVRRLLEN` `________________________________________________________________________________________________________________________` `_________________________________________________________________________________577______586__________________607______` `6x9a(A) : GANSSFVHRINDPKVSIDELIADPVEVVRAMPVVGAKHDRIALPAELFGDARTNSAGLDLSNEETLASLTEALRESAAMKWTALPQLATGPAAGETRTVLNPGDHRDVVGSVTETSEEDA` `:` `9bbo(B) : GANSSFVHRINDPKVSIDELIADPVEVVRAMPVVGAKHDRIALPAELFGDARTNSAGLDLSNEETLASLTEALRESAAMKWTALPQLATGPAAGETRTVLNPGDHRDVVGSVTETSEEDA` `_________________________________________________________________________________577______586__________________607______` `____620_________________________________________________________________________696_700_____________________724__729____` `6x9a(A) : RRAVRLAADAAPDWAAVPPSERAACLDRAAELMQARMPTLLGLIIREAGKSALNAIAEVREAIDFLRYYAEQTRRTLGPGHGPLGPIVCISPWNFPLAIFTGQIAAALVAGNPVLAKPAE` `:` `9bbo(B) : RRAVRLAADAAPDWAAVPPSERAACLDRAAELMQARMPTLLGLIIREAGKSALNAIAEVREAIDFLRYYAEQTRRTLGPGHGPLGPIVCISPWNFPLAIFTGQIAAALVAGNPVLAKPAE` `____620_________________________________________________________________________696_700_____________________724__729____` `______742___________756_760______________________________________________809____________________________________________` `6x9a(A) : ETPLIAAEGVRILREAGIPASALQLLPGDGRVGAALVAAAETAGVMFTGSTEVARLIQAQLADRLSPAGRPIPLIAETGGQNAMIVDSSALAEQVVGDVITSAFDSAGQRCSALRVLCLQ` `:` `9bbo(B) : ETPLIAAEGVRILREAGIPASALQLLPGDGRVGAALVAAAETAGVMFTGSTEVARLIQAQLADRLSPAGRPIPLIAETGGQNAMIVDSSALAEQVVGDVITSAFDSAGQRCSALRVLCLQ` `______742___________756_760______________________________________________809____________________________________________` `_______________________________________________________________________________________________________959__964__969____` `6x9a(A) : EDVADRILTMLKGALHELHIGRTDRLSVDVGPVITSEAKDNIEKHIERMRGLGRKVEQIGLASETGVGTFVPPTIIELEKLSDLQREVFGPVLHVIRYRRDDLDRLVDDVNATGYGLTFG` `:` `9bbo(B) : EDVADRILTMLKGALHELHIGRTDRLSVDVGPVITSEAKDNIEKHIERMRGLGRKVEQIGLASETGVGTFVPPTIIELEKLSDLQREVFGPVLHVIRYRRDDLDRLVDDVNATGYGLTFG` `_______________________________________________________________________________________________________959__964__969____` `________________________________1009_1014__1020_______________1039_____________________________________1080___________10` `6x9a(A) : LHTRLDETIAHVTSRIKAGNLYINRNIIGAVVGVQPFGGRGLSGTGPKAGGPLYLGRLVTTAPVPPQHSSVHTDPVLLDFAKWLDGKGARAEAEAARNAGSSSALGLDLELPGPVGERNL` `:` `9bbo(B) : LHTRLDETIAHVTSRIKAGNLYINRNIIGAVVGVQPFGGRGLSGTGPKAGGPLYLGRLVTTAPVPPQHSSVHTDPVLLDFAKWLDGKGARAEAEAARNAGSSSALGLDLELPGPVGERNL` `________________________________1009_1014__1020_______________1039_____________________________________1080___________10` `95__________________________________________________________________________________________________________________1213` `6x9a(A) : YTLHARGRILLVPATESGLYHQLAAALATGNSVAIDAASGLQASLKNLPQTVGLRVSWSKDWAADGPFAGALVEGDAERIRAVNKAIAALPGPLLLVQAASSGEIARNPDAYCLNWLVEE` `:` `9bbo(B) : YTLHARGRILLVPATESGLYHQLAAALATGNSVAIDAASGLQASLKNLPQTVGLRVSWSKDWAADGPFAGALVEGDAERIRAVNKAIAALPGPLLLVQAASSGEIARNPDAYCLNWLVEE` `95__________________________________________________________________________________________________________________1213` `____________________` `6x9a(A) : VSASINTAAAGGNASLMAIG` `:` `9bbo(B) : VSASINTAAAGGNASLMAIG` `____________________`

Morph

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Status: Initialising

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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	3.5
Translation (A)	0.0
Closure (%)	90.7
Bending Residues ( green )	577 - 578 586 - 587 607 - 608 620 - 621 696 - 697 700 - 701 724 - 725 729 - 730 742 - 745 756 - 757 760 - 776 809 - 810 959 - 962 964 - 967 969 - 970 1009 - 1010 1014 - 1016 1020 - 1021 1039 - 1040 1080 - 1081 1095 - 1096 1213 - 1214
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

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