DynDom - Protein Domain Motions

Diol Dehydrase Alpha Subunit

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Diol Dehydrase Alpha Subunit
Conformer 1 (PDB)	7xrk (A)
Conformer 2 (PDB)	1dio (A)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	298	0.35	17 - 18 129 - 130 133 - 221 253 - 253 255 - 260 307 - 308 320 - 324 327 - 327 329 - 331 335 - 341 348 - 352 359 - 523 529 - 538
2	228	0.46	13 - 16 19 - 128 131 - 132 222 - 252 254 - 254 261 - 306 309 - 319 325 - 326 328 - 328 332 - 334 342 - 347 353 - 358 524 - 528

Sequence

`______________16________________________________________________________________________________________________________` `7xrk(A) : RSKRFEALAKRPVNQDGFVKEWIEEGFIAMESPNDPKPSIKIVNGAVTELDGKPVSDFDLIDHFIARYGINLNRAEEVMAMDSVKLANMLCDPNVKRSEIVPLTTAMTPAKIVEVVSHM` `:` `1dio(A) : MRSKRFEALAKRPVNQDGFVKEWIEEGFIAMESPNDPKPSIKIVNGAVTELDGKPVSDFDLIDHFIARYGINLNRAEEVMAMDSVKLANMLCDPNVKRSEIVPLTTAMTPAKIVEVVSHM` `______________16________________________________________________________________________________________________________` `_____128__________________________________________________________________________________________221___________________` `7xrk(A) : NVVEMMMAMQKMRARRTPSQQAHVTNVKDNPVQIAADAAEGAWRGFDEQETTVAVARYAPFNAIALLVGSQVGRPGVLTQCSLEEATELKLGMLGHTCYAETISVYGTEPVFTDGDDTPW` `:` `1dio(A) : NVVEMMMAMQKMRARRTPSQQAHVTNVKDNPVQIAADAAEGAWRGFDEQETTVAVARYAPFNAIALLVGSQVGRPGVLTQCSLEEATELKLGMLGHTCYAETISVYGTEPVFTDGDDTPW` `_____128__________________________________________________________________________________________221___________________` `_________252_____260___________________________________________306__________319__324____331_______341___347__352___358__` `7xrk(A) : SKGFLASSYASRGLKMRFTSGSGSEVQMGYAEGKSMLYLEARCIYITKAAGVQGLQNGSVSCIGVPSAVPSGIRAVLAENLICSSLDLECASSNDQTFTHSDMRRTARLLMQFLPGTDFI` `:` `1dio(A) : SKGFLASSYASRGLKMRFTSGSGSEVQMGYAEGKSMLYLEARCIYITKAAGVQGLQNGSVSCIGVPSAVPSGIRAVLAENLICSSLDLECASSNDQTFTHSDMRRTARLLMQFLPGTDFI` `_________252_____260___________________________________________306__________319__324____331_______341___347__352___358__` `________________________________________________________________________________________________________________________` `7xrk(A) : SSGYSAVPNYDNMFAGSNEDAEDFDDYNVIQRDLKVDGGLRPVREEDVIAIRNKAARALQAVFAGMGLPPITDEEVEAATYAHGSKDMPERNIVEDIKFAQEIINKNRNGLEVVKALAQG` `:` `1dio(A) : SSGYSAVPNYDNMFAGSNEDAEDFDDYNVIQRDLKVDGGLRPVREEDVIAIRNKAARALQAVFAGMGLPPITDEEVEAATYAHGSKDMPERNIVEDIKFAQEIINKNRNGLEVVKALAQG` `________________________________________________________________________________________________________________________` `______________________________________521____528_________________________` `7xrk(A) : GFTDVAQDMLNIQKAKLTGDYLHTSAIIVGDGQVLSAVNDVNDYAGPATGYRLQGERWEEIKNIPGALDPNED` `:` `1dio(A) : GFTDVAQDMLNIQKAKLTGDYLHTSAIIVGDGQVLSAVNDVNDYAGPATGYRLQGERWEEIKNIPGALDPN*` `______________________________________521____528_________________________`

Morph

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Status: Initialising

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	3.5
Translation (A)	0.1
Closure (%)	99.9
Bending Residues ( green )	16 - 19 128 - 133 221 - 222 252 - 255 260 - 261 306 - 309 319 - 320 324 - 329 331 - 332 334 - 335 341 - 342 347 - 348 352 - 353 358 - 359 521 - 524 528 - 529
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

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