DynDom - Protein Domain Motions

Nadph--Cytochrome P450 Reductase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Nadph--Cytochrome P450 Reductase
Conformer 1 (PDB)	3qe2 (A)
Conformer 2 (PDB)	3es9 (A)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	431	1.04	238 - 678
2	167	0.51	71 - 237

Sequence

`________________________________________________________________________________________________________________________` `3qe2(A) : ESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDNALVVFCMATYGEGDPTDNAQDFYDWLQETDVDLSGVKFAVFGLGNKTYEHFNAMG` `:` `3es9(A) : ESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFAVFGLGNKTYEHFNAMG` `________________________________________________________________________________________________________________________` `__________________________________________233___________________________________________________________________________` `3qe2(A) : KYVDKRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWLAVCEHFGVEATsSIRQYELVVHTDIDAAKVYMGEMGRLKSYENQKPPFDAKNPFLAAVTTNRKLNQGTERHLMHLELDIS` `:` `3es9(A) : KYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEA-SSIRQYELVVHEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTANRKLNQGTERHLMHLELDIS` `__________________________________________230___________________________________________________________________________` `________________________________________________________________________________________________________________________` `3qe2(A) : DSKIRYESGDHVAVYPANDSALVNQLGKILGADLDVVMSLNNLDEESNKKHPFPCPTSYRTALTYYLDITNPPRTNVLYELAQYASEPSEQELLRKMASSSGEGKELYLSWVVEARRHIL` `:` `3es9(A) : DSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEESNKKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGKELYLSWVVEARRHIL` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `3qe2(A) : AILQDCPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVVVEYETKAGRINKGVATNWLRAKEPVrALVPMFVRKSQFRLPFKATTPVIMVGPGTGVAPFIGFIQERAWLRQQ` `:` `3es9(A) : AILQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAVEYEAKSGRVNKGVATSWLRAKEP-rALVPMFVRKSQFRLPFKSTTPVIMVGPGTGIAPFMGFIQERAWLREQ` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `3qe2(A) : GKEVGETLLYYGCRRSDEDYLYREELAQFHRDGALTQLNVAFSREQSHKVYVQHLLKQDREHLWKLI-EGGAHIYVCGDARNMARDVQNTFYDIVAELGAMEHAQAVDYIKKLMTKGRYS` `:` `3es9(A) : GKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLNVAFSREQAHKVYVQHLLKRDREHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFGPMEHTQAVDYVKKLMTKGRYS` `________________________________________________________________________________________________________________________` `_____` `3qe2(A) : LDVWS` `:` `3es9(A) : LDVWS` `_____`

Morph

Morph animation in progress.
Status: Initialising

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	96.9
Translation (A)	-2.5
Closure (%)	82.6
Bending Residues ( green )	233 - 245
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

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