DynDom - Protein Domain Motions

Phosphoenolpyruvate-Protein Phosphotransferase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Phosphoenolpyruvate-Protein Phosphotransferase
Conformer 1 (PDB)	2kx9 (A)
Conformer 2 (PDB)	2hwg (A)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	123	1.47	4 - 22 148 - 254
2	123	1.49	23 - 147
3	303	1.32	256 - 571

Sequence

`____________________22__________________________________________________________________________________________________` `2kx9(A) : MISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDD` `:` `2hwg(A) : *ISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHI-lLEDEELEQEIIALIKDKH-tADAAAHEVIEGQASALEELDD` `____________________22__________________________________________________________________________________________________` `______________________145_______________________________________________________________________________________________` `2kx9(A) : EYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMR` `:` `2hwg(A) : EYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAADLTPSETAQLNLKKVLGFITDAGGRTS-tSI-aRSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDK-r` `______________________145_______________________________________________________________________________________________` `___________254__________________________________________________________________________________________________________` `2kx9(A) : AVQEQVASEKAELAKLKDLPAITLDGHQVEVCANIGTVRDVEGAERNGAEGVGLYRTEFLFMDRDALPTEEEQFAAYKAVAEACGSQAVIVRTMDIGGDKELPYMNFPKEENPFLGWRAI` `:` `2hwg(A) : AVQEQVASEKAELAKLKDLPAITLDGHQVEVCANIGTVRDVEGAERNGAEGVGLYRTEFLF-dRDALPTEEEQFAAYKAVAEACGSQAVIVRT-dIGGDKELPY-nFPKEENPFLGWRAI` `___________254__________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `2kx9(A) : RIAMDRREILRDQLRAILRASAFGKLRIMFPMIISVEEVRALRKEIEIYKQELRDEGKAFDESIEIGVMVETPAAATIARHLAKEVDFFSIGTNDLTQYTLAVDRGNDMISHLYQPMSPS` `:` `2hwg(A) : RIA-dRREILRDQLRAILRASAFGKLRI-fP-iISVEEVRALRKEIEIYKQELRDEGKAFDESIEIGV-vETPAAATIARHLAKEVDFFSIGTNDLTQYTLAVDRGND-iSHLYQP-sPS` `________________________________________________________________________________________________________________________` `_____________________________________________________________________________________________` `2kx9(A) : VLNLIKQVIDASHAEGKWTGMCGELAGDERATLLLLGMGLDEFSMSAISIPRIKKIIRNTNFEDAKVLAEQALAQPTTDELMTLVNKFIEEKT` `:` `2hwg(A) : VLNLIKQVIDASHAEGKWTG-cGELAGDERATLLLLG-gLDEFS-sAISIPRIKKIIRNTNFEDAKVLAEQALAQPTTDEL-tLVNKFIEEKT` `_____________________________________________________________________________________________`

Morph

Morph animation in progress.
Status: Initialising

This morph was created using the MorphIt_Pro protein morphing technique.
For more advanced options, right click on the model.

play backwards

pause

play forwards

Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	67.8
Translation (A)	1.5
Closure (%)	83.1
Bending Residues ( green )	22 - 24 145 - 151
Bending Region Analysis

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( yellow )	3
Rotation Angle (deg)	70.6
Translation (A)	3.1
Closure (%)	96.4
Bending Residues ( green )	254 - 262
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

Conformer 1 Contact:
Residue 1 ———› Residue 3

Conformer 2 Contact:
Residue 3 ———› Residue 1

Movement classification: Hinge

PyMOL Script

Download and extract PyMOL PML script file

Download