Pre-Mrna-Splicing Factor Atp-Dependent RNA Helicase Dhx15

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Pre-Mrna-Splicing Factor Atp-Dependent RNA Helicase Dhx15
  Conformer 1
(PDB) 		5xdr (A)
  Conformer 2
(PDB) 		6sh7 (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 565 0.89   117 - 320   323 - 331   346 - 349   351 - 355   373 - 385   400 - 400   404 - 414   424 - 426   429 - 434   440 - 440   449 - 452   460 - 466   470 - 480   482 - 487   492 - 787
2 90 0.8   321 - 322   332 - 345   350 - 350   356 - 372   386 - 399   401 - 403   415 - 423   427 - 428   435 - 439   441 - 448   453 - 459   467 - 469   481 - 481   488 - 491

Sequence


           ________________________________________________________________________________________________________________________ 
 5xdr(A) : *****CINPFTNLPHTPRYYDILKKRLQLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVEYMRSLPGPKRGVACTQPRRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSS 
         :                                                                                                                          
 6sh7(A) : HMLEQCINPFTNLPHTPRYYDILKKRLQLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVEYMRSLPGPKRGVACTQPRRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSS 
           ________________________________________________________________________________________________________________________ 

           _________________________________________________________________________________________320_____328______________345_34 
 5xdr(A) : AKTILKYMTDGMLLREAMNDPLLERYGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKFQIYFDNCPLLTIPGRTHPVEIFYTPEPERDYLEAAIRTVIQIHMCEEE 
         :                                                                                                                          
 6sh7(A) : AKTILKYMTDGMLLREAMNDPLLERYGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKFQIYFDNCPLLTIPGRTHPVEIFYTPEPERDYLEAAIRTVIQIHMCEEE 
           _________________________________________________________________________________________320_____328______________345_34 

           9___355_____________371___________385___________399_403________414______423________434__439__444_____452____459____466__ 
 5xdr(A) : EGDLLLFLTGQEEIDEACKRIKREVDDLGPEVGDIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQ 
         :                                                                                                                          
 6sh7(A) : EGDLLLFLTGQEEIDEACKRIKREVDD--------kIIPLYSTLPPQQQQRIFEPPP------aIGRKVVVSTNIAETSLTI--vVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQ 
           9___355_____________371___________385___________399_403________414______423________434__439__444_____452____459____466__ 

           _________480____487_____________________________________________________________________________________________________ 
 5xdr(A) : RAGRAGRTRPGKCFRLYTEKAYKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLAALNDDGDLTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVL 
         :                                                                                                                          
 6sh7(A) : RAGRAGRTRPGKCFRLYTEKAYKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLAALNDDGDLTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVL 
           _________480____487_____________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 5xdr(A) : SITAMLSVPQCFVRPTEAKKAADEAKMRFAHIDGDHLTLLNVYHAFKQNHESVQWCYDNFINYRSLMSADNVRQQLSRIMDRFNLPRRSSDFTSRDYYINIRKALVTGYFMQVAHLERTG 
         :                                                                                                                          
 6sh7(A) : SITAMLSVPQCFVRPTEAKKAADEAKMRFAHIDGDHLTLLNVYHAFKQNHESVQWCYDNFINYRSLMSADNVRQQLSRIMDRFNLPRRSTDFTSRDYYINIRKALVTGYFMQVAHLERTG 
           ________________________________________________________________________________________________________________________ 

           ____________________________________________________________________________________                                     
 5xdr(A) : HYLTVKDNQVVQLHPSTVLDHKPEWVLYNEFVLTTKNYIRTCTDIKPEWLVKIAPQYYDMSNFPQCEAKRQLDRIIAKLQSKEY                                     
         :                                                                                                                          
 6sh7(A) : HYLTVKDNQVVQLHPSTVLDHKPEWVLYNEFVLTTKNYIRTCTDIKPEWLVKIAPQYYDMSNFPQCEAKRQLDRIIAKLQS***                                     
           ____________________________________________________________________________________                                     

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		7.1
Translation
(A) 		0.0
Closure
(%) 		53.6
Bending Residues
( green ) 		  320 - 323
  328 - 332
  345 - 346
  349 - 351
  355 - 356
  371 - 374
  385 - 386
  399 - 401
  403 - 404
  414 - 415
  423 - 424
  426 - 429
  434 - 435
  439 - 441
  444 - 449
  452 - 453
  459 - 460
  466 - 467
  469 - 470
  480 - 482
  487 - 492
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

PyMOL Script

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