DynDom - Protein Domain Motions

Solute Carrier Family 15 Member 4

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Solute Carrier Family 15 Member 4
Conformer 1 (PDB)	8wx5 (A)
Conformer 2 (PDB)	8jzx (A)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	224	2.16	30 - 320 353 - 362 366 - 370
2	216	1.99	321 - 352 363 - 365 371 - 555

Sequence

`________________________________________________________________________________________________________________________` `8wx5(A) : *********GAFAGRRAACGAVLLTELLERAAFYGITSNLVLFLNGAPFCWEGAQASEALLLFMGLTYLGSPFGGWLADARLGRARAILLSLALYLLGMLAFPLLAAPATRAALCGSAR` `:` `8jzx(A) : RRAAAAAAAAGAFAGRRAACGAVLLTELLERAAFYGITSNLVLFLNGAPFCWEGAQASEALLLFMGLTYLGSPFGGWLADARLGRARAILLSLALYLLGMLAFPLLAAPATRAALCGS--` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `8wx5(A) :` `LLNCTAPGPDAAARCCSPATFAGLVLVGLGVATVKANITPFGADQVKDRGPEATRRFFNWFYWSINLGAILSLGGIAYIQQNVSFVTGYAIPTVCVGLAFVVFLCGQSVFITKPPDGSAF` `:` `8jzx(A) :` `------------aRCCSPATFAGLVLVGLGVATVKANITPFGADQVKDRGPEATRRFFNWFYWSINLGAILSLGGIAYIQQNVSFVTGYAIPTVCVGLAFVVFLCGQSVFI---------` `________________________________________________________________________________________________________________________` `____________________320____________________________351________362_____370_______________________________________________` `8wx5(A) :` `TDMFKILTYSCeEKVEDVKALVKIVPVFLALIPYWTVYFQMQTTYVLQSLHLRIPEISNITTTPHTLPAAWLTMFDAVLILLLIPLKDKLVDPILRRHGLLPSSLKRIAVGMFFVMCSAF` `:` `8jzx(A) :` `---------------eDVKALVKIVPVFLALIPYWTVYFQMQTTYVLQSLHLRIPEISN----pHTLPAAWLTMFDAVLILLLIPLKDKLVDPILRRHGLLPSSLKRIAVGMFFVMCSAF` `____________________320____________________________351________362_____370_______________________________________________` `________________________________________________________________________________________________________________________` `8wx5(A) : AAGILESKRLNLVKEKTINQTIGNVVYHAADLSLWWQVPQYLLIGISEIFASIAGLEFAYSAAPKSMQSAIMGLFFFFSGVGSFVGSGLLALVSIKAIGWMSSHTDFGNINGCYLNYYFF` `:` `8jzx(A) : AAGILESKRLNLVKEKTINQTIGNVVYHAADLSLWWQVPQYLLIGISEIFASIAGLEFAYSAAPKSMQSAIMGLFFFFSGVGSFVGSGLLALVSIKAIGWMSS----gNINGCYLNYYFF` `________________________________________________________________________________________________________________________` `_____________________` `8wx5(A) : LLAAIQGATLLLFLIISVKY` `:` `8jzx(A) : LLAAIQGATLLLFLIISVKYD` `_____________________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	33.3
Translation (A)	1.6
Closure (%)	99.3
Bending Residues ( green )	320 - 322 351 - 355 362 - 363 365 - 366 370 - 371
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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