Ligand-induced domain movement details

Jmol view of liganded conformation 2

Domain Movement

domain 1 is binding domain(fixed in space) domain 2 is binding domain(fixed in space)






  Property   Value
 Conformer 1 1pae(X)
 Conformer 2 1b4s(A)
 Radius gyration for conformer 1 15.36 A
 Radius gyration for conformer 2 14.89 A
 EC Number  
Click here to see the DynDom results or the famliy
 Trigger ligands ADP160
 Trigger ligands in which conformation Conformation  2
 Conformaton with trigger ligands is compact Yes
 Spanning ligands Yes
 Residues in enzyme contacting ligands ARG109  ARG92  ASN119  HIS59  LEU68  LYS16  PHE64  THR98  TYR56  VAL116 
 Residues in extended bending regions contacting ligands Null
 Residues in extended bending regions making H-bonds or salt-bridges with ligands Null
  Residues in extended bending regions with an H-bond between its main chain and ligands Null
Click here to see the details of H-bonds between ligands and enzyme in PDF format generated by LIGPLOT